For Immediate Release:

For Release 7 a.m. EDT
May 22, 2003

Tripos, Inc. Joins CENSA as a New Supporting Supplier Member

Medford, Mass., and ST. LOUIS - May 22, 2003 - CENSA, the Collaborative Electronic Notebook Systems Association, a global market development association, and Tripos, Inc. (Nasdaq: TRPS), a leading provider of drug discovery informatics products and chemistry research, today announced Tripos' initiation into CENSA as a Supporting Supplier Member.

"We are truly delighted to have Tripos as a Supporting Supplier Member," said Dr. Richard Lysakowski, executive director of CENSA. "Supporting Supplier Members work with End User Members to ensure that technologies and methodologies are developed to meet real needs in scientific discovery, product development and collaboration. Tripos has a long history developing tools for the pharmaceutical industry, and its experience will help to enhance CENSA's Collaborative Electronic Research and Development (CeR&D) Program. More importantly, working with key CENSA members like Tripos in a cooperative manner will more collaboratively accelerate software quality and progress for leading-edge chemists, biologists, materials engineers, and others in scientific discovery and product development."

CENSA hosts four meetings each year where organization members and industry leaders get together to tackle the most current and widespread issues related to electronic notebooks. Tripos will attend its first CENSA meeting in June 2003.

"CENSA and Tripos are both dedicated to accelerating progress in the electronic notebooks and collaborative eR&D solutions," said Dr. John P. McAlister, Ph.D., president and chief executive officer of Tripos. "This relationship is important to us because it provides yet another point of contact with end users to ensure our tools are designed to solve the real problems facing researchers. New ideas obtained through CENSA will be particularly helpful as we enhance our Electronic Lab Journal and other offerings. We look forward to being an active member of CENSA."

About CENSA

CENSA, the Collaborative Electronic Notebook Systems Association, is a global market development association where R&D-driven Fortune 500 corporations and leading technology providers work together to automate complex scientific, technical, and business systems that support and drive rapid innovation. In order to leverage and reuse intellectual and organizational capital more effectively, CENSA's collaborative market catalyst programs focus on long-term, enterprise-wide electronic records, electronic notebooks, large-scale scientific data and content warehousing, integration frameworks and tools, and collaborative eR&D solution assembly tools and standards. CENSA is based in Medford, Mass. More information on CENSA and its programs is available at http://www.censa.org/.

About Tripos, Inc.

Tripos (Nasdaq: TRPS) combines leading-edge technology and innovative science to deliver consistently superior chemistry-research products and services for the biotechnology, pharmaceutical and other life science industries. Tripos partners with clients to accelerate and improve the creation of life-enhancing products. Within Tripos' Discovery Informatics (DI) business, the company provides software products and consulting services to develop, manage, analyze and share critical drug discovery information. Within Tripos' Discovery Research (DR) business, Tripos' medicinal chemists and research scientists partner directly with clients in their research initiatives, leveraging state-of-the-art information technologies and research facilities. Headquartered in St. Louis, Mo., Tripos spans the world with global research operations and an international client base. Further information on Tripos can be found at http://www.tripos.com/.

Contacts:
Tripos, Inc.
Jennifer Schroeder
Director, Corporate Communications
(314) 647-8837, ext. 3367
jschroeder@tripos.com

Waggener Edstrom Bioscience
Lisa Osborne
Account Supervisor
(425) 638-7000, ext. 5134
lisao@wagged.com

The Collaborative Electronic Notebook Systems Association
(781) 395-3004, ext 201

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